PAIP1 are highly expressed in many types of cancer (Bi et al., 2021; Guan et al., 2019; Li et al., 2019; Piao et al., 2018; Wang et al., 2019b; Wang et al., 2019c; Xie et al., 2020), inducing liver cancer (Kim et al., 2020). This evidence concerns the gene PAIP1 and liver cancer.