At the same time, in the research conducted by the Yun Chen, TGFBI was also elevated in various kinds of cancers (cholangiocarcinoma, colon adenocarcinoma (COAD), esophageal carcinoma (ESCA), GBM, head and neck squamous cell carcinoma (HNSC), kidney renal clear cell carcinoma (KIRC), kidney renal papillary cell carcinoma (KIRP), liver hepatocellular carcinoma (LIHC), rectum adenocarcinoma (READ), stomach adenocarcinoma (STAD), and thyroid carcinoma), and it also showed a great value in the survival aspects. This evidence concerns the gene TGFBI and colon adenocarcinoma.