Taken together, these data suggest that LBN: i) increases anxiety-like behavior in the EPM and open field primarily in adult male rats, but not in mice; ii) increases anxiety-like behaviors in the light dark box that may be sex-specific and age-dependent in mice (i.e., adolescent females, adult males), although effects are relatively unexplored in rats; and iii) enhances novelty-induced suppression of feeding in adult female rodents. This evidence concerns the gene EVC2 and Anxiety.