GATM and obesity due to melanocortin 4 receptor deficiency: Increased gene expression levels in the VAT of individuals with obesity in comparison to the SAT of this study group were found for CKB (padj. < 0.001 see Figure 5A), CKMT1B (padj. < 0.001; see Figure 5B), and GATM (padj. < 0.001; see Figure 5C).