CASP3 and neoplasm: ST comprised a pH-triggeredtargeting peptide STP (sequence: SKDEEWHKNNFPLSPG)and DEVD peptide sequence linked with an AIEgen of TPE (tetraphenylethylene)for “switch on” fluorescence in response to caspase-3(Figure 1F), whichcould show “switch on” fluorescence during apoptosis.Once accumulated in the tumor acidic environment, peptide STP andTAT were activated, and the nanomicelle was in an “activated”state, which could enhance the cell permeability and further improvethe penetrability of the “activated” STD-NM.