BDNF and neuroblastoma: In cultured human neuroblastoma SH‐SY5Y cells and rat neurons, the synergistic effects of apigenin with BDNF in stimulating the BDNF‐induced neurite outgrowth and protective effect against amyloid‐beta was demonstrated: this synergism was mediated by a direct interaction between BDNF and apigenin, through activating the signaling cascade of high‐affinity BDNF receptor, Trk B.