HOXB4 and lung carcinoma: It turned out that the expressions of B3GNTL1 and HOXD8 were significantly upregulated, while the expression of remaining five genes (HOXB4, ZNF808, ITGA4, PTGER4, and HOXA7) were significantly downregulated in lung cancer tissues (p < 0.01) (Fig. 3a).