IL6 and triple-A syndrome: In addition, we found that the mRNA level of pro-inflammatory factors Il6, Ccl2 and Mmp-2 in the aorta of mice was significantly downregulated by HMEXO, compared with AMEXO (Figure A similar result was obtained for MMP-9 expression in the adventitia and media of the aorta of different groups (Fig. 2D), indicating that HMEXO is more effective in reducing aortic inflammation in AAA mice than AMEXO.