RELA and breast cancer: Given that the activation of p65 mainly relies on its phosphorylation and nuclear translocation [43], we determined the impact of circRNF10 and DHX15 on p-p65 (Ser536) level and the subcellular localization of p65 in BC cells and validated that circRNF10 and DHX15 were an inhibitor and an activator of p65, respectively.