Milluzzo Milluzzo A A Tumminia Tumminia A A Scalisi Scalisi NM NM Insulin degludec in the first trimester of pregnancy: report of two cases Insulin degludec in the first trimester of pregnancy: report of two cases J Diabetes Investig J Diabetes Investig 2018 2018 9 9 3 3 629 629 631 631 10.1111/jdi.12721 10.1111/jdi.12721. This evidence concerns the gene INS and diabetes mellitus.