Thuillier Thuillier P P Alavi Alavi Z Z Kerlan Kerlan V V Long-term safety and efficacy of insulin degludec in the management of type 2 diabetes Long-term safety and efficacy of insulin degludec in the management of type 2 diabetes Diabetes Metab Syndr Obes Targets Ther Diabetes Metab Syndr Obes Targets Ther 2015 2015 8 8 483 483 493 493. Here, INS is linked to diabetes mellitus.