Ziegler Ziegler AG AG Achenbach Achenbach P P Berner Berner R R Oral insulin therapy for primary prevention of type 1 diabetes in infants with high genetic risk: the GPPAD-POInT (global platform for the prevention of autoimmune diabetes primary oral insulin trial) study protocol Oral insulin therapy for primary prevention of type 1 diabetes in infants with high genetic risk: the GPPAD-POInT (global platform for the prevention of autoimmune diabetes primary oral insulin trial) study protocol Bmj Open Bmj Open 2019 2019 9 9 e028578 e028578 6 6. This evidence concerns the gene INS and type 1 diabetes mellitus.