MMP3 and central nervous system cancer: According to Western blotting results, TUSC7 overexpression group had significantly lower expressions of MMP2, MMP3 and MMP9 than NC group, whereas they were obviously elevated after silencing TUSC7, suggesting that TUSC7 could inhibit the migration of glioma cells by degrading MMP2, MMP3 and MMP9 (Figure 7).