In the unadjusted analysis HIV infection was associated with blood groups AB (OR = 1.12, 95% CI 0.99–1.26), B (OR = 1.16, 85% CI 1.08–1.25) and O (OR = 1.09, CI 95% 1.03–1.16) compared to blood group A. HIV positivity was also strongly associated with RhD positive phenotype (OR = 2.14, 95% CI 1.86–2.47). Here, RHD is linked to HIV infectious disease.