Binary Logistic Regression Analysis of the above clinicopathological factors confirmed lymph node metastasis (P = 0.048, OR = 1.490, 95% CI 1.037 to 3.608), HER2 low expression (P = 0.034, OR = 2.713, 95% CI 1.636 to 3.798) and AR positive (P = 0.017, OR = 2.758, 95% CI 1.564 to 4.013) were independent risk factors for pCR in TNBC after neoadjuvant therapy. This evidence concerns the gene ERBB2 and metastatic malignant neoplasm in the lymph nodes.