Univariate analysis showed that T stage (P = 0.034), N stage (P = 0.015), histological grade (P = 0.018), p53 expression (P = 0.023) and AR status (P = 0.011) were the predictive factors of recurrence and metastasis in HR + /HER2- breast cancer. This evidence concerns the gene ERBB2 and breast carcinoma.