In yeast-induced fever rat model [46, 47], the results showed that SFJDC could significantly reduce body temperature, reduce the levels of prostaglandin E2 (PGE2), TNF-α, IL-1α, IL-1β, IL-6, macrophage inflammatory protein 1 Alpha (MIP-1α), cAMP and the ratio of cAMP/cGMP in serum and hypothalamus. The gene discussed is CCL3; the disease is Fever.