Notably, we also see no substantial influence of the mRNA levels of TNFA (HR = 0.648 vs. 0.518) or TGFB (HR = 0.606 vs. 0.563) on the survival effects of carbonic anhydrases (Fig. 11L-O) in HER2-enriched breast cancer. The gene discussed is TGFB1; the disease is breast cancer.