Significant recession or enhancement on cell migration was observed at 12 h (after scratches were made) in tumor cells with low or high SNRPD1 expression (reduced 40% in MCF7 and almost 30% in MDAMB231 for siRNA-mediated SNRPD1 silencing, enhanced 30% in MCF7 and 20% in MDAMB231 for sgRNA-mediated SNRPD1 enhancing, Fig. 4C and E, supplementary Figure 2) but not in cells with altered SNRPE expression (Fig. 4D and F). This evidence concerns the gene SNRPD1 and neoplasm.