SPHK1 and idiopathic pulmonary fibrosis: Those shared DEGs identified in IPF-FB samples mainly indicated invasive signatures in fibrotic diseases (GPNMB, TENM3) (Palisoc et al. 2022; Athwal et al. 2018; Murakami et al. 2010), cell focal adhesion (LIMS1) (Sandfort et al. 2010; Stanchi et al. 2009), cell cycle (MDGA1) (Lu et al. 2008), and angiogenesis (SPHK1) (Wang et al. 2021) (Fig. 2G, H).