Although our results suggest that there is no relationship between H. pylori and urticaria through molecular mimicry, they also do not completely rule out this hypothesis; Schmetzer et al. [27], observed that more than 200 human proteins could be recognized by IgE autoantibodies in patients with urticaria, therefore H. pylori proteins could have molecular mimicry with other proteins that we did not evaluate; nevertheless, not all those autoantibodies are functional, and the 9 proteins included in this study are those that have antibodies with functional studies. Here, IGHE is linked to urticaria.