Additionally, enhanced mitochondrial activity and autoantibody production by long-lived memory B cells in SLE may be facilitated by deficient peroxiredoxin 6 (PRDX6) antioxidant activity [40] and by an intact mitochondrial cardiolipin remodeling enzyme activity provided by tafazzin [41]. Here, PRDX6 is linked to systemic lupus erythematosus.