Flow cytometry and real‐time quantitative PCR results indicated that CD8+ T cells cocultured with M2‐Exos‐cultured glioma cells had lower proliferation and expression of IFN‐γ, TNF‐α, and Gzmb; however, after adding the exosome inhibitor Annexin V or knocking down LINC01232, this phenomenon was reversed (Figure 3b–e). The gene discussed is ANXA5; the disease is central nervous system cancer.