TGFB1 and neoplasm: Studies have reported that TAMs promote tumor angiogenesis and blood‐derived cell metastasis by secreting a large amount of proangiogenic factors, such as vascular endothelial growth factor (VEGF).[33] TAMs can also produce immunosuppressive factors, such as IL‐10, TGFβ, and PGE2, etc., which promote the occurrence and development of tumors by inhibiting the antitumor immune response.