CD8A and cancer: With the GSVA enrichment score difference of > ¦0.2¦ and FDR‐adjusted P‐value < 0.1, we found the enrichment of activated CD8+ T cells, activated dendritic cells (aDC), cytotoxic cells (which includes genes that are highly expressed in activated CD8+ T cells, gamma‐delta T cells and natural killer cells) and exhausted T cells in high‐IP groups across multiple cancer types (Fig. 3A).