Many cancers, including TNBC, become dependent on autophagy as a source of nutrients during tumor growth.[34] In the present study, we first revealed that DDIT4‐AS1 is involved in the regulation of the autophagy in TNBC, and knockdown of DDIT4‐AS1 suppressed autophagy activity of TNBC cells. The gene discussed is DDIT4; the disease is cancer.