The hollow MnO2 loaded with camptothecin (CPT) was coated with a cancer cell membrane to obtain a biomimetic nanozyme/CPT hybrid system.[144] After the hybrid system targeting accumulates in the cancer site, not only can MnO2 with intrinsic CAT‐mimicking activities decompose H2O2 into O2 to enhance the radiotherapy sensitivity of cancer cells but also CPT can block the cell cycle in the radiosensitive phase. The gene discussed is CAT; the disease is cancer.