MPO and acute respiratory distress syndrome: Notably, preclinical studies support the feasibility of this therapeutic hypothesis as the anti-DEspR antibody induces apoptosis in DEspR + neutrophils observed on live cell imaging of macaque neutrophils and promotes neutrophil apoptosis without worsening elevated myeloperoxidase and complement activation levels, as observed in an ex vivo experimental system testing ARDS patient whole blood samples [19].