AD is broadly characterized by an irreversible progressive loss of cognition and memory often accompanied by anxiety‐like behavior as well as the development of hallmark amyloid‐β accumulation, hyperphosphorylated‐Tau aggregation, and neuroinflammation within the brain (Donovan et al., 2018; Jack et al., 2018; Reitz et al., 2011). Here, MAPT is linked to Alzheimer disease.