Finally, monoallelic dominant duplications in the ATAD3 gene cluster locus (containing ATAD3A, ATAD3B, and ATAD3C genes) lead to multisystemic chromosome 1p.36.33 duplication syndrome, ATAD3 gene cluster (MIM#618815) [12, 13] with severe cardiomyopathy, hypotonia and corneal clouding and variable neurological findings including seizures and white-matter, basal ganglia, thalamus or cerebellar changes on brain imaging. This evidence concerns the gene ATAD3C and cardiomyopathy.