Next, we used PCa microarrays to check the protein level correlation between METTL3 and HRAS/MEK2 in human tissues, and found that METLL3 has a strong correlation with these two genes, confirming the existence of the positively correlation between METTL3 and HRAS/MEK2 in CRPC (Fig. 2E, F). The gene discussed is HRAS; the disease is posterior cortical atrophy.