Differentially expressed cytokines ADAMTS13, Eotaxin-1, IL-6, and MIG/CXCL9 are involved in pathways mediating immune modulation or crosstalk among pro-fibrotic cells and have biological plausibility in SSc, SSc-ILD, and IPF. The gene discussed is ADAMTS13; the disease is idiopathic pulmonary fibrosis.