CD40LG and rubella: This seroprevalence study of congenital infections among a cohort of pregnant women in Coatepeque and surrounding areas in Guatemala, identified maternal T. gondii and CMV IgM and IgG seropositivity, rubella IgG seropositivity, IgM seroconversion for T. gondii (1 woman), and IgM reactivation for CMV (8 women).