GAS1 and Hyperglycemia: Our results suggest that since Gas1 is homogeneously expressed in Bowman’s capsule (like NCAM), and because Gas1 is expressed in the RPCs from PND 1 and reaches its highest expression in the adult, and then remains constant, it could negatively regulate RPCs in Bowman’s capsule during postnatal development and in adulthood, because the expression pattern of Gas1 is inverse to the pattern observed for NCAM, and also because the decrease in the expression of Gas1 allows the activation of the RPCs in glomeruli in a model with adult rats with damage due to hyperglycemia [13].