In the KO‐TRAMP mice, Vcan (with a role in cell adhesion and tumour progression; Ricciardelli et al, 1998) and Myb proto‐oncogene (Li et al, 2014) levels, that are markers of prostate metastasis (Edwards, 2012), were increased, which correlated with reduced miR‐669c‐5p, and reduction in miR‐676‐5p correlated with increased expression of insulin‐like growth factor‐1 (Igf1) that promotes cell growth and malignancy (Perry et al, 2017; Fig 6F). Here, VCAN is linked to neoplasm.