In the KO‐TRAMP and A537T‐TRAMP mice, elevated miRNAs resulted in reduction of prognostic markers of prostate cancer and metastasis, such as cysteine dioxygenase 1 (Cdo1; Meller et al, 2016) and tensin 1 (Tns1; Z. Zhu et al, 2020). Here, TNS1 is linked to Familial prostate cancer.