Survival data revealed that higher numbers of A537T‐TRAMP and KO‐TRAMP mice could not survive by 30 weeks of age and beyond 30 weeks a greater number of these mice die as a consequence of their tumours compared with the WT‐TRAMP mice (Fig 1G), indicating that the Elac2 A537T variant can predispose and exacerbate prostate cancer. This evidence concerns the gene ELAC2 and neoplasm.