In samples with matched RNAseq data on the same tumors with DNA methylation, meningiomas with CDKN2A/B deletions had significantly lower CDKN2A mRNA expression compared to CDKN2A/B intact/wt meningiomas in the Toronto cohort, but not in the transcriptomic validation cohort (Fig. 1k, l). Here, CDKN2A is linked to meningioma.