During 14 days of treatment, the tumor growth rate was significantly reduced treated with TPP‐LND@Lip, PD‐L1 monoclonal antibody, and radiotherapy, and the volume inhibition rate was 53.1 ± 22.3%, 31.3 ± 22.8%, and 51.9 ± 10.8%, respectively. Here, CD274 is linked to neoplasm.