In a recent study of triple‐negative breast cancer, D‐mannose inhibited PD‐L1‐mediated DDR and sensitized tumor cells to ionizing radiation.[6c] Radiotherapy up‐regulated the expression of PD‐L1 in nasopharyngeal carcinoma cells and PD‐1 in NK cells. Here, CD274 is linked to nasopharyngeal carcinoma.