GSTM1 and paroxysmal nocturnal hemoglobinuria: Lastly, an analysis of 779 PNH patients treated with ECU from the International PNH Registry found that mean Hb lab values at the most recent follow-up ranged from 10.1 to 10.7 g/dL, depending on the presence of comorbid aplastic anemia, and LDH values ranged from 1.2–1.4 times the upper limit of normal, while ARC values ranged from 162.5–191.2 × 109/L [32].