Sabiosa atropurpurea L. (mourning bride) methanolic extracts, rich in various glycosidic derivatives of apigenin, luteolin, and quercetin, have also been shown to improve doxorubicin toxicity in Caco-2 cells (colorectal adenocarcinoma) as a result of inhibition of P-gp and MRP1 [91]. Here, PGP is linked to colorectal adenocarcinoma.