Finally, we can conclude that the results of the effect of the rs7537605 inside VAV3 gene and the rs28665122 inside SEPS1 gene in our population suggested that the rs7537605 polymorphism may not be the etiologic mutation, if we compare them with different effects that were reported in the other populations, especially if we consider the multifactorial nature of HT. The gene discussed is SELENOS; the disease is hematocrit.