An increase in systemic IL-2, IL-6, and IL-7, granulocyte colony-stimulating factor, C-X-C motif chemokine 10 (CXCL10), chemokine (C-Cmotif) ligand 2 (CCL2), and tumour necrosis factor-α (TNF- α) has been observed in patients with COVID-19.20 Rapid deterioration in COVID-19 patients is associated with a pro-inflammatory cytokine storm. The gene discussed is TNF; the disease is COVID-19.