INS and type 2 diabetes mellitus: Other T2D-associated SNPs have also been identified on JAZF1 (Sollis et al., 2022), many of which have additionally been linked to diabetes-relevant metabolic traits such as insulin secretion (Grarup et al., 2008; Boesgaard et al., 2009; Dai et al., 2022), insulin clearance (Goodarzi et al., 2013), plasma lipid levels (An et al., 2009; Dai et al., 2022) and body weight (Grarup et al., 2008; Kobiita et al., 2020; Zeng et al., 2021).