According to univariate Cox, LASSO, and multivariate Cox regression analysis, 8 m5CRlncRNAs (AC093157.1, LINC00513, AC025171.4, AC090948.2, ZEB1-AS1, AC109449.1, AC009041.3, and LINC02516) were determined to be significant prognostic factors to explore the prognostic function in CRC. Here, ZEB1 is linked to colorectal carcinoma.