Previous research has shown that the three pathways “Rig I like receptor”, “Pathways in cancer”, and “T cell receptor signaling pathway” (Figures 3B–D) play an important role in hepatitis B fibrosis and subsequent development into hepatocellular carcinoma (Yao et al., 2021; Chen et al., 2023; Zhang et al., 2023). The gene discussed is TBXT; the disease is hepatocellular carcinoma.