The results indicate that the lysosomal DEG-related pathway is mainly associated with ommunition and coagulation cascades that Staphylococcus aureus infection, Viral protein interaction with cytokine and cytokine receptor, the Lysosome, ECM-receptor interaction, IL-17 signaling pathway, Chemokine signaling pathway Amoebiasis, Proteoglycans in cancer, pathway, Pertussis, Malaria, and Cytokine-cytokine receptor interaction were related. This evidence concerns the gene IL17A and malaria.