On the other hand, downregulation of UQCRB expression inhibited the tumour stem cell-like properties of human glioblastoma cells, and synthetic small molecule drugs targeting UQCRB significantly inhibited the self-renewal capacity, migration and invasion of U87MG and U373MG-derived glioblastoma stem-like cells (GSCs)(39). This evidence concerns the gene UQCRB and glioblastoma.