CRP and osteoarthritis: We observed the effects of YQYXF and celecoxib (Cxb) on visual analogue scale (VAS) score, swelling, range of motion (ROM) and joint function, Michel Lequesen index of severity for osteoarthritis (ISOA) score, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Kellgren-Lawrence score, erythrocyte sedimentation rate (ESR) and c-reactive protein (CRP) index of KOA patients (Kellgren and Lawrence, 1957; Brosseau et al., 2003; Zhang et al., 2009; Anil et al., 2021).