CSF2 and autoimmune disease: Among the eight key genes identified for AAV kidney injury, CSF2 is involved in the pathogenesis of several inflammatory and autoimmune diseases, and play an essential role in regulating the pro-inflammatory function of monocytes in the pathogenesis of AAV-related renal injury (Krebs et al., 2017; VVilar et al., 2020; Rousselle et al., 2022).