AMACR and Familial prostate cancer: AMACR, GOLM1, TRPM8 and NKX3-1-overexpressed,associated with disease, aggressiveness,extracapsular extension,tumor stage,vesicular seminal invasionGOLM1, TRPM8 and NKX3-1-identification of high-risk prostate cancer with high sensitivity and specificityNKX3-1-Prostate cell differentiation,Prostate cancer initiation, (loss of function),high gradeprostate cancer (overexpression)TRPM8-cell migration andtumor progression