Compared with patients without MAFLD, CD patients with MAFLD had significantly higher BMI (P < 0.001), percentage of hypertension (P=0.004), percentage of hyperlipidemia (P=0.002), AST (P=0.010), ALT (P < 0.001), GGT (P < 0.001), TG (P < 0.001), C-peptide (P=0.013) levels, and a lower HDL level (P < 0.001). The gene discussed is GPT; the disease is hyperlipidemia.