The statistically significant variables in Table 4 were used as independent variables, and whether or not the posterior circulation was positively remodelled was used as the dependent variable in a one-way binary logistic regression analysis (Model C), which showed that diabetes (OR = 0.253, 95% CI: 0.087–0.739, p = 0.012), YKL-40 (OR = 1.061, 95% CI: 1.018 ~ 1.106, p = 0.005), MMP-9 (OR = 1.024, 95% CI: 1.008–1.041, p = 0.003) and integrated indicator (OR = 3.711, 95% CI: 1.921 ~ 7.168, p < 0.01) were risk factors for positive remodelling of the posterior circulation. Here, CHI3L1 is linked to diabetes mellitus.