In the present study, we decided to focus on LOXL4 among the LOX family proteins because of the unusual increase in LOXL4 (among all of the LOX family members) in MDA-MB-231 breast cancer cells, which is consistent with those in other TNBC cell lines; in addition, this finding is in agreement with the results described by Choi et al. This evidence concerns the gene LOX and breast cancer.